Thursday, July 24, 2008

Brand Name: Zoloft
Generic Name: Sertraline
(ser' tra leen)

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Why is zoloft prescribed?How should zoloft be used properly?What are the common uses for zoloft?What special precautions should I follow when using zoloft?What special dietary instructions should I follow while taking zoloft? What should I do if I forget a dose of zoloft?What side effects can zoloft cause?What storage conditions are needed for zoloft?What do I do in case of emergency or an zoloft overdose?What other information should I know about zoloft?

Why is zoloft prescribed?

Zoloft (Sertraline) is used to treat depression, obsessive-compulsive disorder, panic attacks, and posttraumatic stress disorder. It is also used to relieve the symptoms of premenstrual dysphoric disorder, including mood swings, irritability, bloating, and breast tenderness. Zoloft is in a class of medications called selective serotonin reuptake inhibitors (SSRIs). It works by increasing the amounts of serotonin, a natural substance in the brain that helps maintain mental balance.

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How should zoloft be used properly?

Sertraline (Zoloft) comes as a tablet and a concentrate (liquid) to take by mouth. It is usually taken once daily in the morning or evening. To treat premenstrual dysphoric disorder, sertraline is taken once a day, either every day of the month or on certain days of the month. To help you remember to take sertraline, take it around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take sertraline exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Sertraline concentrate must be diluted before use. Immediately before taking it, use the provided dropper to remove the amount of concentrate your doctor has directed you to take. Mix the concentrate with 4 ounces (1/2 cup) of water, ginger ale, lemon or lime soda, lemonade, or orange juice. Do not mix the concentrate with any liquids other than the ones listed. Drink immediately.

Your doctor may start you on a low dose of sertraline and gradually increase your dose, not more than once a week.

It may take a few weeks or longer before you feel the full benefit of sertraline. Continue to take sertraline even if you feel well. Do not stop taking sertraline without talking to your doctor.

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What are the common uses for zoloft?

Sertraline is also used sometimes to treat social phobia, headaches, and sexual problems. Talk to your doctor about the possible risks of using this medication for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

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What special precautions should I follow when using zoloft?

Before taking sertraline,

  • tell your doctor and pharmacist if you are allergic to sertraline or any other medications. Before taking sertraline liquid concentrate, tell your doctor if you are allergic to latex.
  • do not take sertraline if you are taking monoamine oxidase (MAO) inhibitors, including phenelzine (Nardil) and tranylcypromine (Parnate), or have stopped taking them within the past two weeks, or if you are taking pimozide (Orap).
  • do not take disulfiram (Antabuse) while taking sertraline concentrate.
  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. Be sure to mention any of the following: anticoagulants ('blood thinners') such as warfarin (Coumadin); antidepressants (mood elevators) such as amitriptyline (Elavil), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Adapin, Sinequan), imipramine (Tofranil), nortriptyline (Aventyl, Pamelor), protriptyline (Vivactil), and trimipramine (Surmontil); cimetidine (Tagamet); diazepam (Valium); digoxin (Lanoxin); lithium (Eskalith, Lithobid); medications for anxiety, mental illness, Parkinson's disease, and seizures; medications for irregular heartbeat such as flecainide (Tambocor) and propafenone (Rythmol); oral medications for diabetes such as tolbutamide (Orinase); sedatives; sleeping pills; sumatriptan (Imitrex); and tranquilizers. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • tell your doctor if you have recently had a heart attack and if you have or have ever had seizures, bipolar disorder, or liver or heart disease.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking sertraline, call your doctor.
  • you should know that sertraline may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you.
  • ask your doctor about the safe use of alcoholic beverages while you are taking sertraline.

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What should I do if I forget a dose of zoloft?

You should take the missed dose of zoloft just as soon as you remember to take it. Unless,  it is almost time for the next dose, then skip the missed dose and resume your regular dosing schedule. Never take a double dose of your medication to make up for a missed one.

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What side effects can zoloft cause?

Sertraline may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • burning, or tingling in the hands or feet
  • difficulty falling asleep or staying asleep
  • changes in sex drive or ability
  • uncontrolable hand shaking
  • excessive tiredness
  • excessive sweating
  • weight changes
  • loss of appetite
  • upset stomach
  • bloating or gas
  • nervousness
  • constipation
  • drowsiness
  • excitement
  • sore throat
  • dry mouth
  • headache
  • dizziness
  • vomiting
  • diarrhea 

Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately:

  • hallucinating, seeing things or hearing voices that do not exist
  • abnormal bleeding or bruising
  • blurred vision
  • seizure

Sertraline may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

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What storage conditions are needed for zoloft?

Always keep the zoloft in the same container it came in. Make sure it is tightly closed, and out of reach of children. Store this medication at room temperature and away from excess heat and moisture; do not store this medication in the bathroom. 

Always be sure to dispose of any medication that is no longer needed or outdated. Be sure to ask your pharmacist about the proper disposal of your medication.

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What do I do in case of emergency or an zoloft overdose?

In case of an zoloft overdose, be sure to call your local poison control center at 1-800-222-1222. If the victim is not breathing or has collapsed, dial 911 for local emergency services.

Symptoms of overdose may include:

  • hallucinating, hearing voices or seeing things that do not exist
  • difficulty falling asleep or staying asleep
  • rapid pounding or irregular heartbeat
  • changes in sex drive or ability
  • uncontrolable hand shaking
  • excessive tiredness
  • unconsciousness
  • upset stomach
  • drowsiness
  • excitement
  • dizziness
  • hair loss
  • seizures
  • vomiting
  • diarrhea
  • fainting

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What other information should I know about zoloft?

Keep all appointments with your doctor.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

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This document is provided for information only. It is not a substitute for consultation with a physician, either to diagnose symptoms or prescribe treatment. Any dosages mentioned are general guidelines only; please follow the directions of your doctor or pharmacist exactly when taking medication. We have made every effort to ensure that this information is accurate, but only your doctor can say if a medication, or drug combination, is safe for you. Information intended for US residents only.

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